ЭПИДЕМИОЛОГИЯ, ЭТИОПАТОГЕНЕЗ МИОКАРДИТА, ВЫЗВАННОГО COVID-19


  • Ахмедова Г.А., Зиядуллаев Ш.Х., Расулов С.К.
    Самаркандский государственный медицинский институт, Республика Узбекистан, г. Самарканд

Abstract

В этой статье представлена информация об эпидемиологии и этиопатогенезе миокардита, вызванного covid 19, матриксной металлопротеиназой и ее ингибиторами. 11 марта 2020 года ВОЗ объявила пандемию тяжелого острого респираторного синдрома (SARS) коронавируса 2 (SARS-CoV-2), в результате чего был введен термин коронавирусная болезнь (2019) (COVID-19). Источник SARS-CoV-2 еще точно не идентифицирован, но есть предположения о зоонозной природе инфекции.

Keywords

матриксная металапротиеназа, тканевый ингибитор, миокардит, Covid-19

Literature

Chen T., Wu D., Chen H., et al. Clinical characteristics of 113 deceased patients with coronavirus disease 2019: retrospective study. BMJ. Mar 26 2020;368:m1091.

Finlay B. B., See R. H., Brunham R. C. Rapid response research to emerging infectious diseases: lessons from SARS. Nat. Rev. Microbiol. 2004;2(7):602–607.

Huang C., Wang Y., Li X., Ren L, Zhao J., Hu Y., et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395(10223):497–506. https://doi.org/10.1016/S0140-6736(20)30183-5

Jain A. COVID-19 and lung pathology. Indian J. Pathol. Microbiol. 2020;63:171–172.

Liu PP, Blet A, Smyth D, Li H. The Science Underlying COVID-19: Implications for the Cardiovascular System. Circulation. 2020; circulationaha.120.047549. [Epub ahead of print]. DOI: 10.1161/CIRCULATIONAHA.120.047549

Mahmud E., Dauerman H. L., Welt F. G., Messenger J. C., Rao S. V., Grines C., et al. Management of Acute Myocardial Infarction During the COVID-19 Pandemic. Journal of the American College of Cardiology. 2020. https://doi. org/10.1016/j.jacc.2020.04.039

Manish Bansal. Cardiovascular disease and COVID-19. Diabetes & Metabolic Syndrome: Clinical Research & Reviews. 2020;14:247–250. https://doi.org/10.1016/j.dsx.2020.03.013

Walls A. C., Park Y. J., Tortorici M. A., Wall A., McGuire A. T., Veesler D. Structure, function, and antigenicity of the SARS-CoV-2 spike glycoprotein. Cell. 2020;180:1–12.

Zhao D., Yao F., Wang L., Zheng L., Gao Y., Ye J., et al. A comparative study on the clinical features of COVID-19 pneumonia to other pneumonias. Clin. Infect. Dis. 2020; ciaa 247. https://doi.org/10.1093/cid/ciaa24

. Costabel U., du Bois R. M., Egan J. J. (eds.) Diffuse Parenchymal Lung Disease. Prog. Respir. Res. 2007;36:1–10.

Aguiar D., Lobrinus J. A., Schibler M., Fracasso T., Lardi1 C. Inside the lungs of COVID-19 disease. International Journal of Legal Medicine. 2020;(134):1271–1274. https://doi.org/10.1007/s00414-020-02318-9

Arentz M., Yim E., Klaff L., et al. Characteristics and outcomes of 21 critically ill patients with COVID-19 in Washington State. JAMA. 2020 [Epub ahead of print].

Bangalore S, Sharma A, Slotwiner A, Yatskar L, Harari R, Shah B et al. ST-Segment Elevation in Patients with Covid-19 – A Case Series. New England Journal of Medicine. 2020;NEJMc2009020. [Epub ahead of print]. DOI: 10.1056/NEJMc2009020

Caforio ALP, Pankuweit S, Arbustini E, Basso C, Gimeno-Blanes J, Felix SB et al. Current state of knowledge on aetiology, diagnosis, management, and therapy of myocarditis: a position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases. European Heart Journal. 2013;34(33):2636–48. DOI: 10.1093/eurheartj/eht210

Chan J. F., Yuan S., Kok K. H., To K. K., Chu H., Yang J., et al. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster. Lancet. 2020;395(10223):514–523. https://doi.org/10.1016/ S0140-6736(20)30154-9 3. Ghinai I., McPherson T. D., H.

Coutard B., Valle C., de Lamballerie X., Canard B., Seidah N. G., Decroly E. The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade. Antivir. Res. 2020;176:104742. https://doi.org/10.1016/j.antiviral.2020.104742

Craver R, Huber S, Sandomirsky M, McKenna D, Schieffelin J, Finger L. Fatal Eosinophilic Myocarditis in a Healthy 17-Year-Old Male with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2c). Fetal and Pediatric Pathology. 2020;1–6. [Epub ahead of print]. DOI: 10.1080/15513815.2020.1761491

Craver R., Huber S., Sandomirsky M., McKenna D., Schieffelin J., Finger L. Fatal Eosinophilic Myocarditis in a Healthy 17-Year-Old Male with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2c). =Fetal Pediatr. Pathol. 2020:1–6. https://doi.org/10.1080/15513815.2020. 1761491. [Epub ahead of print].

Ghinai I., McPherson T. D., Hunter J. C., Kirking H. L., Christiansen D., et al. Illinois COVID-19 Investigation Team. First known person-to-person transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the USA. Lancet. 2020;S0140-6736(20)):30607–3. https://doi.org/10.1016/S0140-6736(20)30607-3

Guzik T. J., et al. COVID-19 and the cardiovascular system implications for risk assessment, diagnosis, and treatment options. Cardiovascular Research. 2020. https:// doi.org/10.1093/cvr/cvaa106

Hoffmann M., Kleine-Weber H., Schroeder S., Krüger N., Herrler T., Erichsen S., et al. SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor. Cell. 2020;181:1–10.

Inciardi RM, Lupi L, Zaccone G, Italia L, Raffo M, Tomasoni D et al. Cardiac Involvement in a Patient With Coronavirus Disease 2019 (COVID-19). JAMA Cardiology. 2020; [Epub ahead of print]. DOI: 10.1001/jamacardio.2020.1096

Katzenstein F.-L. Diagnostic atlas of non-neoplastic lung disease. A practical guide for surgical pathologist. New York, NY: Demos Medical Publishing, 2016.

Kim I-C, Kim JY, Kim HA, Han S. COVID-19-related myocarditis in a 21-year-old female patient. European Heart Journal. 2020;41(19):1859–1859. DOI: 10.1093/eurheartj/ehaa288

Kochi A. N., Tagliari A. P., Forleo G. B., Fassini G. M., Tondo C. Cardiac and arrhythmic complications in patients with COVID‐19. J CardiovascElectrophysiol. 2020;31:1003–1008. https://doi.org/10.1111/jce.14479

Liu P. P., Blet A., Smyth D., Li H. The Science Underlying COVID-19: Implications for the Cardiovascular System. Circulation. 2020 Apr 15. https://doi.org/10.1161/CIRCULATIONAHA.120.047549. [Epub ahead of print].

Long B., Brady W. J., Koyfman A., et al. Cardiovascular complications in COVID-19. American Journal of Emergency Medicine. https://doi.org/10.1016/j. ajem.2020.04.048

Park W. B., Kwon N. J., Choi S.J., Kang C. K., Choe P. G., Kim J. Y., et al. Virus isolation from the first patient with SARS-CoV-2 in Korea. J. Korean Med. Sci. 2020;35(7):e84. https://doi.org/10.3346/jkms.2020.35.e84

Paul J-F, Charles P, Richaud C, Caussin C, Diakov C. Myocarditis revealing COVID-19 infection in a young patient. European Heart Journal - Cardiovascular Imaging. 2020;jeaa107. [Epub ahead of print]. DOI: 10.1093/ehjci/jeaa107

Perrella A., Trama U., Bernardi F. F., Russo G., Monastra L., Fragranza F., et al. Editorial — COVID-19, more than a viral pneumonia. European Review for Medical and Pharmacological Sciences. 2020;24:5183–5185.

Pomara C., Volti G. L., Cappello F. COVID-19 Deaths: Are We Sure It Is Pneumonia? Please, Autopsy, Autopsy, Autopsy! J. Clin. Med. 2020;9:1259. https://doi.org/10.3390/ jcm9051259

Rey JR, Jiménez Valero S, PovedaPinedo D, Merino JL, LópezSendón JL, Caro-Codón J. COVID-19 y trombosissimultáneaen dos arteriascoronarias. Revista Española de Cardiología. 2020; [Epub ahead of print]. DOI: 10.1016/j.recesp.2020.05.004

Sala S, Peretto G, Gramegna M, Palmisano A, Villatore A, Vignale D et al. Acute myocarditis presenting as a reverse Tako-Tsubo syndrome in a patient with SARS-CoV-2 respiratory infection. EuropeanHeartJournal. 2020;41(19):1861–2. DOI: 10.1093/eurheartj/ehaa286

Sala S., Peretto G., Gramegna M., Palmisano A., Villatore A., Vignale D., et al. Acute Myocarditis Presenting as a Reverse Tako-Tsubo Syndrome in a Patient With SARS-CoV-2 Respiratory Infection. Eur. Heart J. 2020;41(19):1861–1862. https://doi.org/10.1093/eurheartj/ehaa286

Thygesen K, Alpert JS, Jaffe AS, Chaitman BR, Bax JJ, Morrow DA et al. Fourth universal definition of myocardial infarction (2018). European Heart Journal. 2019;40(3):237–69. DOI: 10.1093/eurheartj/ehy462

Thygesen K., Alpert J. S., Jaffe A.S., Chaitman B. R., Bax J. J., Morrow D. A., et al. ESC Scientific Document Group. Fourth universal definition of myocardial infarction (2018). Eur Heart J. 2019;40(3):237–269. https://doi. org/10.1093/eurheartj/ehy462

Wallace A.H., Simpson J., Hirani N. Spencer’s pathology of the lung. Vol. 1. Ed. Ph. Hasleton, D.B. Frieder. Acute lung injury. Cambridge: Cambridge University Press. 2013;1:342–365.

Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J et al. Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus – Infected Pneumonia in Wuhan, China. JAMA. 2020;323(11):1061–9. DOI: 10.1001/jama.2020.1585.

World Health Organization Coronavirus disease 2019 (COVID-19) situation report—51. World Health Organization, 2020. https://www.who.int/docs/default-source/ coronaviruse/situationreports/20200311-sitrep-51-covid-19.pdf?sfvrsnј1ba62e57_10

Wrapp D., Wang N., Corbett K. S., Goldsmith J. A., Hsieh C. L., Abiona O. et al. Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation. Science. 2020;367(6483):1260–1263. https://doi.org/10.1126/ science.abb2507

Xiong T. Y., Redwood S., Prendergast B., Chen M. Coronaviruses and the cardiovascular system: acute and longterm implications. European Heart Journal. 2020;0:1–3. https://doi.org/10.1093/eurheartj/ehaa231

Xiong Y., Sun D., Liu Y., Fan Y., Zhao L., Li X., Zhu W. Clinical and high-resolution CT features of the COVID-19 infection: comparison of the initial and follow-up changes. Investig. Radiol. 2020.

Xu Z, Shi L, Wang Y, Zhang J, Huang L, Zhang C et al. Pathological findings of COVID-19 associated with acute respiratory distress syndrome. The Lancet Respiratory Medicine. 2020;8(4):420–2. DOI: 10.1016/S2213-2600(20)30076-X

Yao XH, Li TY, He ZC, Ping YF, Liu HW, Yu SC et al. A pathological report of three COVID-19 cases by minimal invasive autopsies. Chinese Journal of Pathology. 2020;49(5):411–7. DOI: 10.3760/ cma.j.cn112151-20200312-00193

Zheng Y.-Y., Yi M.-T., Zhang J. -Y., Xie X. COVID-19 and the cardiovascular system. Nature reviews. 2020;17:259–260.

Zheng Y-Y, Ma Y-T, Zhang J-Y, Xie X. COVID-19 and the cardiovascular system. Nature Reviews Cardiology. 2020;17(5):259–60. DOI: 10.1038/s41569-020-0360-5

Download (Русский)
  • Pushlish date: 3.12.2021
  • DOI:

  • Release: 3 ( 2021 ). Problems of biology and medicine
  • Section: Review of the literature


  • Копировать