• Абдуллаева У.К., Сулаймонова Г.Т., Мухамеджанова М.Х., Эргашев Б.Б.
  Бухарский государственный медицинский институт, Республика Узбекистан, г. Бухара

Abstract

Представлены общие сведения о коронавирусах, хроника эпидемии COVID-2019, вызванной коронавирусом SARS-CoV-2, и оценка глобальной эпидемической ситуации. Приведены рекомендации национальных регуляторных органов и Всемирной организации здравоохранения по лечению заболеваний и септического шока, вызванных SARS-CoV-2, в том числе целевые значения системной гемодинамики у пациентов, перечень рекомендуемых лекарственных средств, способы их применения и ограничения фармакотерапии.

Keywords

коронавирус; коронавирусная инфекция; COVID-2019; SARS-CoV-2; 2019-nCoV; пневмония; лечение; безопасность.

Literature

1. Покровский ВИ, Киселев ОИ, Назаров ПГ. SARS: тяжелый острый респираторный синдром. Новый вирус, новая болезнь. Цитокины и воспаление. 2003;2(2):42–51.

2. Paules CI, Marston HD, Fauci AS. Coronavirus infections— more than just the common cold. JAMA. 2020;323(8):707–8.

3. Liu J, Zheng X, Tong Q, Li W, Wang B, Sutter K, et al. Overlapping and discrete aspects of the pathology and pathogenesis of the emerging human pathogenic coronaviruses SARS-CoV, MERS-CoV, and 2019-nCoV. J Med Virol. 2020. [Epub ahead of print]

4. Guan WJ, Ni ZY, Hu Y, Liang WH, Ou CQ, He JX, et al. Clinical Characteristics of Coronavirus Disease 2019 in China. N Engl J Med. 2020.

5. The Novel Coronavirus Pneumonia Emergency Response Epidemiology Team. The Epidemiological Characteristics of an Outbreak of 2019 Novel Coronavirus Diseases (COVID-19) — China, 2020. China CDC Weekly. 2020;2(8):113–22.

6. Røsjø H, Varpula M, Hagve TA, Karlsson S, Ruokonen E, Pettilä V, et al. Circulating high sensitivity troponin T in severe sepsis and septic shock: distribution, associated factors, and relation to outcome. Intensive Care Med. 2011;37(1):77–85.

7. Shalhoub S, Farahat F, Al-Jiff ri A, Simhairi R, Shamma O, Siddiqi N, Mushtaq A. IFN-α2a or IFN-β1a in combination with ribavirin to treat Middle East respiratory syndrome coronavirus pneumonia: a retrospective study. J Antimicrob Chemother. 2015;70(7):2129–32.

8. ARDS Defi nition Task Force, Ranieri VM, Rubenfeld GD, Thompson BT, Ferguson ND, Caldwell E, et al. Acute respiratory distress syndrome: the Berlin Defi nition. JAMA. 2012;307(23):2526–33.

9. Riviello ED, Kiviri W, Twagirumugabe T, Mueller A, BannerGoodspeed VM, Offi cer L, et al. Hospital incidence and outcomes of the acute respiratory distress syndrome using the Kigali modifi cation of the Berlin defi nition. Am J Respir Crit Care Med. 2016; 193(1):52–9.

10. Alshahrani MS, Sindi A, Alshamsi F, Al-Omari A, El Tahan M, Alahmadi B, et al. Extracorporeal membrane oxygenation for severe Middle East respiratory syndrome coronavirus. Ann Intensive Care. 2018;8(1):3.

11. Combes A, Brodie D, Bartlett R, Brochard L, Brower R, Conrad S, et al. Position paper for the organization of extracorporeal membrane oxygenation programs for acute respiratory failure in adult patients. Am J Respir Crit Care Med. 2014;190(5):488–96.

12. Schmidt GA, Girard TD, Kress JP, Morris PE, Ouellette DR, Alhazzani W, et al. Offi cial executive summary of an American Thoracic Society/American College of Chest Physicians clinical practice guideline: liberation from mechanical ventilation in critically ill adults. Am J Respir Crit Care Med. 2017;195(1):115–9.

13. Klompas M, Branson R, Eichenwald EC, Greene LR, Howell MD, Lee G, et al. Strategies to prevent ventilator-associated pneumonia in acute care hospitals: 2014 update. Infect Control Hosp Epidemiol. 2014;35(8):915–36.

14. Naimovna S.G., Kurbanovna A.U., Shukurloevna N.M., Jabborovna A.I. Evaluation of the gastrointestinal mucosa by the OLGA system in chronic atrophic gastritis, // Journal of Critical Reviews 7 (2), 409-413

15. Karimov M.M., Sobirova G.N., Abdullayeva U.K. Chronic gastritis and carcinogenesis issues Herald of Pancreatic Club 45 (4), 65-70

16. Sobirova G.N., Abdullaeva U.K. Immunopatogenesis of chronic gastritis and its role in carcinogenesis 1 (4), 20-27

17. Abdullaeva U.K. Predicting the risk of atrophic transformation in chronic gastritis using serum pepsinogen World journal of pharmaceutical research, Faculty of Pharmacy Medical 8 (13) 219-228

18. Sobirova G.N., Abdullaeva U.K. Chronic gastritis and carcinogenesis issues Central Asian Problems of Modern Science and Education 4 (2), 159-172