• Давлатов С.С., Хамдамов Б.З.
  Бухарский государственный медицинский институт, Республика Узбекистан, г. Бухара

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Аннотация

Сахарный диабет (СД) в мире признан одной из наиболее важных неинфекционных болезней, распространение которой приобрело характер пандемии. В списке поздних осложнений СД лидирует синдром диабетической стопы, приводя к ранней инвалидизации и определяя высокий уровень летальности. В 2019 г. диабет стал непосредственной причиной 1,5 миллиона случаев смерти, и 48% всех связанных с диабетом случаев смерти произошли в возрасте до 70 лет. По данным Международной диабетической федерации, от 25 до 47% госпитализаций больных СД связано с гнойно-деструктивными поражениями стоп вследствие развития хронической ишемии тканей. В обзоре отражены основные патофизиологические механизмы возникновения нарушения микроциркуляции при синдроме диабетической стопы, приводящие к критической ишемии нижних конечностей.

Ключевые слова

сахарный диабет, синдром диабетической стопы, микроангиопатия, макроангиопатия, ишемия, микро-циркуляция.

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