• Абдашимов З.Б., Ходжибекова Ю.М., Юнусова Л.Р.
  1 – Самаркандский государственный медицинский университет, Республика Узбекистан, г. Самарканд; 2 – Ташкентский государственный стоматологический институт, Республика Узбекистан, г. Ташкент

Аннотация

Rhino-orbito-cerebral mucormycosis (ROCM) has emerged in epidemic proportions, triggering a new health challenge in world. ROCM, an angioinvasive infection, is caused by the filamentous fungi of the family of Mucoraceae. Predisposing factors include uncontrolled diabetes, hematologic malignancies, solid-organ and stem cell transplantations, use of corticosteroids, and an immunocompromised status. There has been a substantial rise in the number of patients with mucormycosis in Uzbekistan during the COVID-19 pandemic. ROCM is predominantly seen in patients with diabetes/prediabetes in whom COVID-19 infection increases the risk of complications and fatality. Computed tomography (CT) in ROCM has a relatively lesser role as compared with magnetic resonance imaging (MRI), which has overall better soft-tissue resolution to assess disease extension.

Ключевые слова

Rhino-orbito-cerebral mucormycosis, CT, MRI, COVID-19.

Литература

1. Petrikkos G, Skiada A, Lortholary O, Roilides E, Walsh TJ, Kontoyiannis DP. Epidemiology and clinical manifestations of mucormycosis. Clin Infect Dis. 2012;54(suppl 1):S23-S34.

2. Mehta S, Pandey A. Rhino-orbital mucormycosis associated with COVID-19. Cureus. 2020;12.

3. Mazzai L, Anglani M, Giraudo C, Martucci M, Cester G, Causin F. Imaging features of rhinocerebral mucormycosis: from onset to vascular complications. Acta Radiol. 2022;63:232-244.

4. Sarkar S, Gokhale T, Choudhury SS, Deb AK. COVID-19 and orbital mucormycosis. Indian J Ophthalmol. 2021;69:1002-1004.

5. Singh AK, Singh R, Joshi SR, Misra A. Mucormycosis in COVID-19: a systematic review of cases reported worldwide and in India. Diabetes Metab Syndr. 2021;15:102146.

6. Safder S, Carpenter JS, Roberts TD, Bailey N. The “black turbinate” sign: an early MR imaging finding of nasal mucormycosis. Am J Neuroradiol.2010;31:771-774.

7. Han Q, Escott EJ. The Black Turbinate Sign, A potential diagnostic pitfall: evaluation of the normal enhancement patterns of the nasal turbinates.Am J Neuroradiol. 2019;40:855-861.

8. Khazratov, A. I., Rizaev, J. A., Lisnychuk, N. Y., Reimnazarova, G. D., Kubaev, A. S., & Olimjonov, K. J. (2021). Morphofunctional Characteristics Of The Oral Mucosa Of Experimental Rats In Experimental Carcinogenesis. European Journal of Molecular and Clinical Medicine, 8(2), 227-235.

9. Indiran V. “Guitar pick sign” on MRI. Indian J Ophthalmol. 2019;67:1737.

10. Rizaev J. A., Khaidarov N. K., Abdullaev S. Y. Current approach to the diagnosis and treatment of glossalgia (Literature review) // World Bulletin of Public Health. – 2021. – Т. 4. – С. 96-98.

11. Rizaev J. A., Rizaev E. A., Akhmadaliev N. N. Current view of the problem: A new approach to COVID-19 treatment // Indian Journal of Forensic Medicine & Toxicology. – 2020. – Т. 14. – №. 4. – С. 7341-7347.

12. Rizaev J. A., Maeda H., Khramova N. V. Plastic surgery for the defects in maxillofacial region after surgical resection of benign tumors //Annals of Cancer Research and Therapy. – 2019. – Т. 27. – №. 1. – С. 22-23.

13. Rizaev J. A., Kuliev O. A. Risk factors of anemia in children and prognosing of it // Электронный инновационный вестник. – 2018. – №. 4. – С. 62-65.

14. Rizaev J. A., Shodmonov A. A. Optimization of the surgical stage of dental implantation based on computer modeling //World Bulletin of Public Health. – 2022. – Т. 15. – С. 11-13.

15. Rizaev J. A., Bekmuratov L. R. Prevention of tissue resorption during immediate implant placement by using socket shield technique // Art of Medicine. International Medical Scientific Journal. – 2022. – Т. 2. – №. 3.

16. Rizaev J. A. et al. Peculiarities of the Dynamics of Morbidity of allergic Diseases among Children of Tashkent // Annals of the Romanian Society for Cell Biology. – 2021. – С. 15309-15319.

17. Rizaev J. A. Features of the aggressive forms of periodontitis course // International Journal of Bio-Science and Bio-Technology. – 2019. – Т. 11. – №. 7. – С. 10-16.